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Green Tea May Interfere With Antihypertensive

Small, early study found reduced blood levels of nadolol among green tea drinkers
TUESDAY, Jan. 14, 2014 (HealthDay News) -- Drinking green tea may lessen the effects of the antihypertensive medication nadolol (Corgard), according to research published online Jan. 13 in Clinical Pharmacology & Therapeutics.
Shingen Misaka, Ph.D., from Fukushima Medical University in Japan, and colleagues gave 10 volunteers a single dose of 30 milligrams of nadolol after they had consumed either water or about three cups of green tea daily for 14 days.
The researchers found that blood levels of the drug were 76 percent lower in the group that drank green tea compared to the water-drinking group.
"Individuals who take nadolol and also consume green tea should be aware of this potential interaction and discuss this with their physician," Gregg Fonarow, M.D., a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association, told HealthDay. He reviewed the findings but did not take part in the study.
Abstract (http://www.nature.com/clpt/journal/vaop/naam/abs/clpt2013241a.html )Full Text (subscription or payment may be required) (http://www.nature.com/clpt/journal/vaop/naam/pdf/clpt2013241a.pdf )
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