About Us  |  Contact Us  |  Español
VNA of Care New England
VNA of Care New England

Urinary Albumin Linked to More Heart Disease in Blacks

Higher heart disease risk found only for a first heart disease event
TUESDAY, Aug. 20 (HealthDay News) -- A high urinary albumin-to-creatinine ratio at baseline is associated with a higher risk of a first coronary heart disease (CHD) event in blacks compared with whites, with no racial differences in the risk of a recurrent CHD event, according to a study published in the Aug. 21 issue of the Journal of the American Medical Association.
Orlando M. Gutierrez, M.D., M.M.Sc., from the University of Alabama at Birmingham, and colleagues examined the association between the urinary albumin-to-creatinine ratio and the risk of CHD based on race in two groups: incident CHD among 23,273 participants without CHD at baseline, and first recurrent CHD event among 4,934 participants with CHD at baseline.
Over a median of 4.4 years of follow-up, the researchers noted 616 incident CHD events and 468 recurrent CHD events. After adjusting for several factors, a higher urinary albumin-to-creatinine ratio at baseline was associated with a significantly higher risk of incident CHD among black subjects (hazard ratio [HR], 3.21 for highest versus lowest ratio) but not white subjects (HR, 1.49). In contrast, there were no differences in the risk of recurrent CHD among blacks (HR, 2.21) and whites (HR, 2.48).
"Higher urinary albumin-to-creatinine ratio was associated with greater risk of incident but not recurrent CHD in black individuals when compared with white individuals," Gutierrez and colleagues conclude.
Several authors disclosed financial relationships with pharmaceutical companies, including Amgen, which partly funded the study.
Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1730510#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1730510 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1730494 )
Health Headlines
Certain Sedatives Tied to Breathing Problems in Older COPD PatientsView in a lightbox
Appetite, Taste Changes Reported After Weight-Loss SurgeryView in a lightbox
Happy Couples Nestle Together at Night, Survey FindsView in a lightbox
Health Highlights: April 18, 2014View in a lightbox
Health Tip: Avoid Driving During Flood WarningView in a lightbox
VNA of Care New England
© 2011 Site Index | Disclaimer | Legal Notices