About Us  |  Contact Us  |  Español
VNA of Care New England
VNA of Care New England

Dietary Fiber Intake Linked to Reduced Gastric Cancer Risk

Meta-analysis shows lower odds of gastric cancer for highest versus lowest intake of dietary fiber
MONDAY, July 22 (HealthDay News) -- Dietary fiber intake is inversely associated with gastric cancer risk and is likely independent of conventional risk factors, according to a meta-analysis published in the July issue of Gastroenterology.
Zhizhong Zhang, from the Nanjing University School of Medicine in China, and colleagues conducted a literature review to identify case-control and cohort studies that assessed the correlation between dietary fiber intake and gastric cancer risk. Twenty-one articles were analyzed, which included 580,064 subjects. Summary relative risks were estimated using random-effects models.
The researchers found that, for the highest versus the lowest dietary fiber intake, the summary odds ratios of gastric cancer was 0.58, with significant heterogeneity identified among studies (I², 62.2 percent). Consistent results were seen on stratified analysis accounting for study design, geographic area, source and type of fiber, Lauren's classification, publication year, sample size, and study quality score. A significant, 44 percent reduction in gastric cancer risk was seen for each 10-g/day increment in fiber intake. Similar results were seen on restriction of sensitivity analysis to studies controlling for conventional risk factors. There was little effect on the combined risk estimate with omission of any single study.
"In a meta-analysis, we show that dietary fiber intake is associated inversely with gastric cancer risk; the effect probably is independent of conventional risk factors," the authors write. "The direction of the protective association of dietary fiber was consistent among all studies, but the absolute magnitude was less certain because of heterogeneity among the studies."
Abstract (http://www.gastrojournal.org/article/S0016-5085(13)00492-7/abstract )Full Text (subscription or payment may be required) (http://www.gastrojournal.org/article/S0016-5085(13)00492-7/fulltext )
Health Headlines
Health Tip: Eat HealthyView in a lightbox
Health Tip: Keep Your Kitchen CleanView in a lightbox
Athletic Trainers First Line of Treatment for Young Basketballers: StudyView in a lightbox
People Seek Out Health Info When Famous Person DiesView in a lightbox
Early Sign of Kidney Disease Often Ignored, Study SaysView in a lightbox
VNA of Care New England
© 2011 Site Index | Disclaimer | Legal Notices